Lung Cancer in Women: The Differences in Epidemiology, Biology and Treatment Outcomes

Maria Patricia Rivera

Expert Rev Resp Med. 2009;3(6):627-634.

Chronic Obstructive Lung Disease & Lung Cancer Risk

Although chronic obstructive pulmonary disease (COPD) has been linked to lung cancer risk in several studies,^[52,53] the link between lung cancer and COPD has not been well studied in women. Recent data from a case–control study of 562 women with NSCLC and 564 control women evaluated the relationship between COPD and risk of lung cancer.^[54] In this study, an increased risk of lung cancer associated with a history of COPD was found among white women (OR: 1.85) but this increased risk was not seen among African–American women. Emphysema diagnosed within 9 years of lung cancer was associated with substantial risk (OR: 6.36). Interestingly, the risk between COPD and lung cancer was not seen in never-smokers (OR: 0.34).^[54]

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Cite this: Lung Cancer in Women: The Differences in Epidemiology, Biology and Treatment Outcomes - Medscape - Dec 01, 2009.

Abstract
Cigarette Smoking & Lung Cancer Risk
Are Women at Increased Risk for Developing Lung Cancer?
Molecular Aberrations
Growth Factor Receptors
Biological Differences
DNA Repair Capacity
Hormonal Differences
Human Papillomavirus Infection
Chronic Obstructive Lung Disease & Lung Cancer Risk
Histologic Distribution of Lung Cancer in Women
Lung Cancer Treatment Outcomes in Women
Expert Commentary
Five-year View
References
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