Lung Cancer in Women: The Differences in Epidemiology, Biology and Treatment Outcomes

Maria Patricia Rivera


Expert Rev Resp Med. 2009;3(6):627-634. 

In This Article

Chronic Obstructive Lung Disease & Lung Cancer Risk

Although chronic obstructive pulmonary disease (COPD) has been linked to lung cancer risk in several studies,[52,53] the link between lung cancer and COPD has not been well studied in women. Recent data from a case–control study of 562 women with NSCLC and 564 control women evaluated the relationship between COPD and risk of lung cancer.[54] In this study, an increased risk of lung cancer associated with a history of COPD was found among white women (OR: 1.85) but this increased risk was not seen among African–American women. Emphysema diagnosed within 9 years of lung cancer was associated with substantial risk (OR: 6.36). Interestingly, the risk between COPD and lung cancer was not seen in never-smokers (OR: 0.34).[54]


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