Are We Getting Closer to the Treatment of Rabies?

Rodney E Willoughby Jr


Future Virology. 2009;4(6):563-570. 

In This Article


Rabies was one of the first vaccine preventable diseases, yet it remains the world's most important zoonosis for reasons of financial disparity. Advances in rabies biologicals finally promise to make rabies prevention economically accessible to all. With improvements in survival during human rabies, we are increasing our understanding of the unique pathophysiology and immunology of this highly fatal viral encephalitis. Therapeutic animal models are under development and clinical trials will follow. As the science improves, we expect our findings to generalize to diagnostic and therapeutic approaches beneficial to other infectious neurological disorders.