For patients with either NSTEMI or STEMI, American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend that intravenous unfractionated heparin (UFH) be dosed by weight with a bolus dose of 60 U/kg to a maximum of 4000 U and an infusion dose of 12 U/kg/h to a maximum of 1000 U/h.
As such, the quality metric used in the ACTION site report looks at the proportion of patients with excess dosing, defined as initial UFH bolus dose > 70 U/kg or infusion dose > 15 U/kg/h. Refer to site reports for STEMI (Slide 1) and NSTEMI (Slide 2).
STEMI Report (N=79 pts) Q3 2007
NSTEMI Report (N=115 pts) Q3 2007
Cardiosource © 2009 American College of Cardiology
© 2006 American College of Cardiology
Cite this: Karen P. Alexander. Excess Unfractionated Heparin Dosing for STEMI and NSTEMI - Medscape - Jun 15, 2009.