Key Articles and Guidelines Relative to Intensive Care Unit Pharmacotherapy: 2009 Update

Brian L. Erstad, Pharm.D., FCCM, FCCP, FASHP; Gretchen M. Brophy, Pharm.D., FCCP, FCCM; Steven J. Martin, Pharm.D., FCCP, FCCM; Curtis E. Haas, Pharm.D., FCCP; John W. Devlin, Pharm.D., FCCM, FCCP; Lynda S. Welage, Pharm.D., FCCP; William E. Dager, Pharm.D., FCSHP, FCCP, FCCM


Pharmacotherapy. 2009;29(10):1228-1269. 

In This Article

Economic Benefits of Intensive Care Unit Pharmacy Services

MacLaren R, Bond CA, Martin SJ, Fike D. Clinical and economic outcomes of involving pharmacists in the direct care of critically ill patients with infections. Crit Care Med 2008;36:3184–9.

Moffett BS, Mott AR, Nelson DP, Gurwitch KD. Medication dosing and renal insufficiency in a pediatric cardiac intensive care unit: impact of pharmacist consultation. Pediatr Cardiol 2008;29:744–8.

Meidi TM, Woller TW, Iglar AM, Brierton DG. Implementation of pharmacy services in a telemedicine intensive care unit. Am J Health Syst Pharm 2008;65:1464–9.

Ng TMH, Hong C, Hara JM, et al. Pharmacist monitoring of QTc interval–prolonging medications in critically ill patients: a pilot study. Ann Pharmacother 2008;42:475–82.

Kopp BJ, Mrsan M, Erstad BL, Duby JJ. Cost implications of and potential adverse events prevented by interventions of a critical care pharmacist. Am J Health Syst Pharm 2007;64:2483–7.

Patel NP, Brandt CP, Yowler CJ. A prospective study of the impact of a critical care pharmacist assigned as a member of the multidisciplinary burn care team. J Burn Care Res 2006;27:310–13.

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Gandhi PJ, Smith BS, Tataronis GR, et al. Impact of a pharmacist on drug costs in a coronary care unit. Am J Health Syst Pharm 2001;58:497–503.

Leape LL, Cullen DJ, Clapp MD, et al. Pharmacist participation on physician rounds and adverse drug events in the intensive care unit. JAMA 1999;282:267–70.

White CM, Chow MS. Cost impact and clinical benefits of focused rounding in the cardiovascular intensive care unit. Hosp Pharm 1998;33:419–23.

Baldinger SL, Chow MS, Gannon RH, Kelly ET. Cost savings from having a clinical pharmacist work part-time in a medical intensive care unit. Am J Health Syst Pharm 1997;54:2811–14.

Devlin JW, Holbrook AM, Fuller HD. The effect of ICU sedation guidelines and pharmacist interventions on clinical outcome and drug costs. Ann Pharmacother 1997;31:689–95.

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Chuang LC, Sutton JD, Henderson GT. Impact of a clinical pharmacist on cost saving and cost avoidance in drug therapy in an intensive care unit. Hosp Pharm 1994;29:215–21.

Rosenbaum CL, Fant WK, Miyagawa CI, Armistead JA. Inability to justify a part-time clinical pharmacist in a community hospital intensive care unit. Am J Health Syst Pharm 1991;48:2154–7.

Katona BG, Ayd PR, Walters JK, Caspi M, Finkelstein BW. Effect of a pharmacist's and a nurse's interventions on cost of drug therapy in a medical intensive care unit. Am J Hosp Pharm 1989;46:1179–82.

Bearce WC, Willey GA, Fox RL, Coleman LT. Documentation of clinical interactions: quality of care issues and economic considerations in critical care pharmacy. Hosp Pharm 1988;23:883–90.

Dasta JF, Armstrong DK. Pharmacoeconomic impact of critically ill surgical patients. Drug Intell Clin Pharm 1988;22:994–8.

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Miyagawa CI, Rivera JO. Effect of pharmacist interventions on drug therapy costs in a surgical intensive care unit. Am J Hosp Pharm 1986;43:3008–13.

Herfindal ET, Bernstein LR, Kishi DT. Impact of clinical pharmacy services on prescribing on a cardiothoracic-vascular surgical unit. Drug Intell Clin Pharm 1985;19:440–4.