Resveratrol -- Apocryphal Claim or Promise?

Désirée Lie, MD, MSEd

Disclosures

October 20, 2009

Case Presentation

Mr. X, a 45-year-old bank manager, has a family history of Alzheimer's and cardiovascular disease. His 69-year-old mother has early Alzheimer's disease and his father died at age 55 years of a myocardial infarction. In addition, his 48-year-old brother was recently diagnosed with colorectal cancer. Mr. X is anxious about his risk for these diseases, although he has a normal body mass index and blood pressure, receives an annual physical examination, does not smoke, eats a heart-healthy diet, and undergoes 120-150 minutes of moderate-intensity aerobic exercise weekly. He drinks 1-2 glasses of wine daily with dinner. He plans to have a colonoscopy this year. Yet, he would like to do more to lower his disease risk.

He heard of resveratrol, a substance found in wine, from a reputable television program and researched resveratrol on the Internet. He now believes resveratrol has antiaging properties that protect against Alzheimer's disease, cardiovascular disease, and cancer. He would like to know where to purchase this supplement and what dose to take for maximum protective effect to counteract his health risks.

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