Other Organ Involvement
As we alluded to previously, AIP seems to be the pancreatic manifestation of a systemic disease. AIP can present with other organ involvement. The initial presentation and the subsequent recurrences can vary depending on the organ involved. Common organs to be involved are the bile ducts (stricture and stenosis), salivary glands (Sjögren's-like syndrome), retroperitoneal fibrosis, lymph nodes, the renal parenchyma and orbital pseudotumors.[6,24,25,26,66] In addition, there are reports suggesting lung and prostate involvement as well. Bile duct involvement, which is reported in 90-100% of cases, is the most common extrapancreatic manifestation.[24,25,26] The bile ducts can be involved in multiple ways, as discussed previously. In addition to the other organ involvement, there is evidence to suggest that other autoimmune conditions, such as inflammatory bowel diseases, are seen at a much higher rate than the general population.
Expert Rev Gastroenterol Hepatol. 2009;3(2):197-204. © 2009 Expert Reviews, Ltd.
Cite this: Autoimmune Pancreatitis: An Update - Medscape - Apr 01, 2009.