Autoimmune Pancreatitis: An Update

Aravind Sugumar; Suresh Chari

Disclosures

Expert Rev Gastroenterol Hepatol. 2009;3(2):197-204. 

In This Article

Expert Commentary & Five-year View

In our opinion, the problem of AIP/ISD treatment requires a multipronged investigation approach. Research into this approach is currently ongoing. Scientists are trying to better understand the pathogenesis and antigenic triggers involved. The role of IgG4 in AIP in particular, whether is it involved in the pathogenesis or is a bystander, is still unclear. Clinical research conducted over the next 5 years should concentrate on combining resources to conduct prospective trials to elucidate the natural history, treatment protocols and guidelines on management of relapses.

All the while, we hope that there will be continued improvements in imaging quality. MRI holds a great deal of promise for the future. It will be interesting to see if the advent of EUS elastography and intraductal ultrasound of the pancreas adds to the diagnostic armamentarium.

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