Age-related Associations of Hypertension and Diabetes Mellitus with Chronic Kidney Disease

Tareq M Islam; Caroline S Fox; Devin Mann; Paul Muntner


BMC Nephrology 

In This Article


In conclusion, hypertension and diabetes mellitus are associated with stage 3 or 4 CKD and albuminuria across the full adult age range. Importantly, this association was statistically significantly stronger at younger age groupings. The low overall prevalence of stage 3 or 4 CKD among adults <50 years of age may mask the increased risk of CKD among individuals with hypertension or diabetes mellitus. Further research is needed to better define the differential impact of risk factors for the development of stage 3 or 4 CKD and albuminuria by age group. Additionally, studies aimed at the identification of novel risk factors for stage 3 or 4 CKD and albuminuria, especially among older adults, are warranted.