In patients with non diabetic nephropathies (mainly glomerular diseases) and deteriorated renal function, the original Cockcroft and Gault formula, the BSA-modified Cockcroft and Gault formula, the abbreviated MDRD equation and the Mayo Quadratic equation give reliable estimates of the GFR slope with an acceptable bias. In the subgroup of patients with an improvement in renal function, these creatinine-based formulas underestimate the gain in GFR although this may have less important clinical consequences.
Guy Rostoker, e-mail: firstname.lastname@example.org
The authors declare that they have no competing interests.
GR has contributed to the conception and design of the study, statistical analysis, interpreting the data, reporting of the work and wrote the article. PA supervised and performed the analysis of the glomerular filtration rate and interprétation of data. IP supervised and performed the analysis of the glomerular filtration rate and interprétation of data. MG performed the statistical analysis, tables, figures. SA has contributed to the planning, conduct and critical analysis of the report and revising of the article
This work was supported by Association Quincy Recherche Clinique et Thérapeutique, Centre Hospitalier Privé Claude Galien, and Compagnie Générale de Santé.
BMC Nephrology © 2009
Cite this: Accuracy and Limitations of Equations for Predicting the Glomerular Filtration Rate during Follow-up of Patients with Non-diabetic Nephropathies - Medscape - Jun 25, 2009.