Childhood- and adult-onset lupus: an update of similarities and differences

Eva D Papadimitraki, MD, PhD; David A Isenberg, MD, FRCP, FACS


Expert Rev Clin Immunol. 2009;5(4):391-403. 

In This Article

Expert Commentary & Five-year View

Systemic lupus erythematosus presenting in adults and children shows important differences with respect to the prevalence of clinical and serological features. Furthermore, childhood-onset disease presents particular problems with respect to treatment complications and adherence. The next 5 years will see the reporting of drug trials of a variety of new biological agents that have good potential to reduce the burden of disease in both adults and children with SLE.


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