Tracheobronchomalacia in Children

Ian Brent Masters; Anne Bernadette Chang

Disclosures

Expert Rev Resp Med. 2009;3(4):425-439. 

In This Article

Pathophysiology

Malacia disorders are predominantly disorders of airway resistance. In a dynamic sense, the expiratory phase is worse but the variable nature of the lesions in pediatrics lends to partial airway closure such that inspiration is also affected in many cases. The site and severity of obstruction results in ventilation perfusion (V/Q) mismatch, and obstructive hypoventilation may also occur.[102] Concomitant pathology, such as bronchitis, atelectasis, pneumonia and local gas trapping, may compound the basic pathophysiology.

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