XPG mRNA Expression Levels Modulate Prognosis in Resected Non-small-cell Lung Cancer in Conjunction With BRCA1 and ERCC1 Expression

Roberta Bartolucci; Jia Wei; Jose Javier Sanchez; Laia Perez-Roca; Imane Chaib; Francesco Puma; Raffaele Farabi; Pedro Mendez; Fausto Roila; Tatsuro Okamoto; Miquel Taron; Rafael Rosell

Disclosures

Clin Lung Cancer. 2009;10(1):47-52. 

In This Article

Conclusion

In summary, the present study validates the prognostic value of BRCA1 in early-stage NSCLC[8] and identifies XPG as a modulator of the risk of recurrence in patients with high BRCA1 mRNA levels. These findings could have important implications for the optimal use of adjuvant chemotherapy.

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