Epidemiological and Genetic Factors Associated With Ovarian Cancer

Monica R. McLemore, RN, MPH; Christine Miaskowski, RN, PhD, FAAN; Bradley E. Aouizerat, PhD, MAS; Lee-may Chen, MD; Marylin J. Dodd, RN, PhD, FAAN


Cancer Nurs. 2009;32(4):281-288. 

In This Article

Risk Factors

A number of epidemiological studies have evaluated a variety of risk factors for ovarian cancer. To date, these risk factors include age,[1,16,20] chronic inflammation, nonsteroidal anti-inflammatory drug (NSAID) use,[24,25,26,27,28] diet,[29,30,31,32,33,34,35,36,37,38,39] ethnicity,[9,18,19] hormone replacement therapy (HRT),[9,16,17,40,41] hysterectomy,[17,42] infertility drug use,[43,44,45,46,47] obesity,[48,49,50] OCP use,[13,16,17,20] parity (pregnancy),[13,15,16] smoking,[51,52,53,54,55,56,57,58,59] and talc use/asbestos exposure.[60,61,62,63,64] The following sections summarize published data on these risk factors for ovarian cancer.


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