Obesity is an important modifiable risk factor in the development and progression of renal disease in children, especially those with suspected low nephron endowment such as those born preterm or SGA. Many of these children are predisposed to insulin resistance and develop excessive weight during infancy that may have long-term implications for later disease. If they have genetic predisposition to renal disease or have lost renal mass, their risk becomes more significant.
Pediatr Health. 2009;3(2):141-153. © 2009 Future Medicine Ltd.