Treatment of Acute Myeloid Leukemia With Hematopoietic Stem Cell Transplantation

Cortney V. Jones; Edward A. Copelan

Disclosures

Future Oncol. 2009;5(4):559-568. 

In This Article

Prognostic Factors in AML

Numerous prognostic factors have been identified in patients with AML. These include age, performance status, white blood count at diagnosis, number of induction cycles required to obtain complete remission, presence of an antecedent hematologic disorder, a history of prior radiation or chemotherapy and cytogenetic analysis.[26,27,28,29,30,31] While prognostication is important, those factors that can be used to help select specific treatment based on their differential effect on outcome following different treatments are most useful. Cytogenetics are the most powerful predictor of outcome and are most useful in selecting postremission therapy.[26,27,28,29,30,31,32,33]

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