Treatment of Acute Myeloid Leukemia With Hematopoietic Stem Cell Transplantation

Cortney V. Jones; Edward A. Copelan

Disclosures

Future Oncol. 2009;5(4):559-568. 

In This Article

Autologous Transplantation in First Complete Remission

Despite recent and ongoing studies in which autologous transplants are an integral part of 'standard' therapy, there is no convincing data demonstrating superior survival compared with appropriate post-remission chemotherapy or allogeneic transplant in any circumstance.[42,43,46] In addition, autologous transplantation in first remission may prevent or increase the risk of later allotransplantation in patients who relapse.[46] While it is reasonable to study autotransplant in selected patients in first remission, its routine use is not justified.

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