The Importance of Iron in Long-Term Survival of Maintenance Hemodialysis Patients Treated With Epoetin-Alpha and Intravenous Iron: Analysis of 9.5 Years of Prospectively Collected Data

Victor E. Pollak; Jonathan A. Lorch; Rakesh Shukla; Supriya Satwah


BMC Nephrology 

In This Article


  • In HD patients a high Hb level (> 120 g/L) was associated with the best survival, a relatively low Hb level (≤ 110 g/L) with the worst.

  • With respect to parameters reflecting iron status, the best survival was associated with a high serum iron (> 10.7 μmol/L), TSAT (> 25%), and serum ferritin (> 600 μg/L), the worst with low levels for all three measurements.

  • The influence of IV iron on survival was profound. The best survival was in patients receiving 1–202 mg per month, the worst in patients receiving no IV iron at all, and in those receiving > 455 mg per month.

  • The influence of EPO on survival was very small, but the best survival was in patients receiving EPO ≤ 12.1 103 units per week.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.