Comparison of Markers of Oxidative Stress, Inflammation and Arterial Stiffness Between Incident Hemodialysis and Peritoneal Dialysis Patients – An Observational Study

Robert G. Fassett; Ritza Driver; Helen Healy; Dwarakanathan Ranganathan; Sharad Ratanjee; Iain K. Robertson; Dominic P. Geraghty; James E. Sharman; Jeff S. Coombes


BMC Nephrology 

In This Article


The objective of this study is to assess whether peritoneal dialysis will have less effect on arterial stiffness, vascular function, myocardial structure and function, oxidative stress and inflammation than hemodialysis. Comparing the effects of renal replacement therapy modalities on surrogate cardiovascular markers over time will provide unique important information to assist in the treatment of patients with ESKD. Data from this trial may also lead to a larger scale study assessing the effect of dialysis modality on major cardiovascular endpoints.


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