A Review of Collagen and Collagen-based Wound Dressings

David Brett, BS, BS, MS

Disclosures

Wounds. 2008;20(12) 

In This Article

Conclusion

Previously, collagens were thought to function only as structural support; however, collagen and collagen-derived fragments control many cellular functions, including cell shape and differentiation, migration, and synthesis of a number of proteins. Collagen also plays a critical role in all phases of wound healing (hemostasis, inflammation, proliferation, and remodelling). It is also clear that while much of the MoA of the various collagen dressings is similar, there are key differences as well.

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