Levothyroxine Use in Infants and Children with Congenital or Acquired Hypothyroidism

Contributing Editor: Marcia L. Buck, Pharm.D.; Editorial Board: Kristi N. Hofer, Pharm.D.; Michelle W. McCarthy, Pharm.D.


Pediatr Pharm. 2008;14(10) 

In This Article


Levothyroxine is available as Synthroid® (Abbott) as well as a number of generic products. Most manufacturers market a wide variety of tablet strengths to allow for dose titration, including 25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200, and 300 mcg. For infants and young children, the tablets may be crushed and mixed into a small amount of water. It should not be mixed with infant formula or breast milk. An extemporaneous formulation for making an oral suspension is also available.[15] Levothyroxine injection is available in 200 mcg/10 mL and 500 mcg/10 mL vials.[2,3]


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