Adenosine for the Management of Neonatal and Pediatric Supraventricular Tachycardia

Contributing Editor: Marcia L. Buck, Pharm.D.; Editorial Board: Kristi N. Hofer, Pharm.D.; Michelle W. McCarthy, Pharm.D.


Pediatr Pharm. 2008;14(8) 

In This Article

Adverse Effects

The most frequent adverse effects reported after adenosine administration include transient arrhythmias at the time of cardioversion (reported in up to 55% of patients in clinical trials), facial flushing (18%), shortness of breath (12%), a feeling of pressure in the chest (7%), nausea (3%), headache and dizziness (both in 2%). Less common effects include: chest pain, transient alterations in blood pressure, sweating, numbness and tingling in the arms, apprehension, hyperventilation, blurred vision, a burning sensation, as well as neck, back, groin and arm pain, a metallic taste in the mouth, and tightness of the throat (all reported in < 1% of patients). Isolated cases of seizures occurring after adenosine administration have been reported to the manufacturer.[3,4]


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