Incidental Placental Choriocarcinoma in a Term Pregnancy: A Case Report

Christopher Chung; Ming-Shian Kao; Deborah Gersell


J Med Case Reports 

In This Article


It is not a routine practice to send a placenta for pathological evaluation following a normal spontaneous delivery. However, a number of cases, like ours, reported incidental findings of placental choriocarcinoma in asymptomatic mothers and infants with no evidence of metastases. In the majority of these cases, the placenta was sent to pathology due to other pregnancy complications such as intrauterine growth restriction, pre-eclampsia, maternal fetal hemorrhage, and in our case, gestational hypertension. It is our belief that the incidence of placental choriocarcinoma may actually be higher than reported. It is also well established that early detection and treatment of gestational trophoblastic disease improves treatment outcome. The obstetrician, pathologist and pediatrician should have an increased awareness of placental choriocarcinoma and its manifestations. Clinical suspicion and any gross placental anomaly should mandate a thorough pathological examination of the placenta.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as: