Race-based Therapy for Hypertension: Possible Benefits and Potential Pitfalls

Keith C. Ferdinand; Daphne P. Ferdinand


Expert Rev Cardiovasc Ther. 2008;10(6):1357-1366. 

In This Article

Five-year View

In the future, the concept of race will be utilized less and become less acceptable as a means of describing populations in scientific research, compared with ancestry. Furthermore, genetic testing and genomics will identify single nucleotide polymorphisms that may or may not be more common in certain self-identified populations. This approach will use ancestry to assist with detailing the response, potential complications and benefit of antihypertensive and cardiovascular medicines in individuals, regardless of self-identified race or ethnicity.

The importance of changing adverse environmental conditions and the widespread implementation of therapeutic lifestyle changes will be emphasized. Socioeconomic status and health systems factors, such as universal access to healthcare, assistance with cost of medication, improvement in the application of evidence-based medication and therapeutic lifestyle changes, will become increasingly important components of modern medical care related to hypertension.

Specific means to identify which patients may develop untoward complications of care, including angioedema with ACEIs, will become an increasing area of interest as true genetic-based research is refined.


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