Nutrigenomics and Personalized Nutrition: Science and Concept

Martin Kussmann; Laurent B. Fay

Disclosures

Personalized Medicine. 2008;5(5):447-455. 

In This Article

Conclusion & Future Perspective

Nutrition and health research and its implementation into food products will become increasingly personalized as the ability of scientific tools to distinguish important physiological differences merges with the industrial means to deliver individual solutions. This process is not a revolution of food, but rather reflects the continued diversification of foods that has been ongoing for centuries. Practical solutions for most consumers will benefit by focusing food personalization on validated nutritional solutions to established subsets of the population. Infants, pregnant and lactating women, active or sedentary adults, athletes, frail elderly and consumers who suffer from inherited or acquired diseases all represent large consumer groups with food requirements that both address their nutritional issues and ensure compliance by considering personal preferences in taste, texture and appearance. Developing nutritional foods to help diseased people recover should accompany the parallel approaches in personalized medicine.

The genomics sciences have delivered proof of the principle that humans are different with respect to optimal diets. As nutrigenomics and nutrigenetics build the scientific foundation for this, and as genotyping technologies become readily accessible, consumers may gain value through information on their personal genetic code. However, only those genetic variations should be assessed that can be adequately addressed by appropriate diets.

However, humans are not only genetically different. This highlights the necessary synergies between the genotyping and the holistic investigations of the metabolism deploying transcriptomics, proteomics and metabolomics, the latter three providing insights into how diet and health alter the expression or 'manifestation' of our genomes.

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