Pain in Women With Relapsing-remitting Multiple Sclerosis and in Healthy Women: A Comparative Study

Pamela Newland

Disclosures

J Neurosci Nurs. 2008;40(5):262-268. 

In This Article

Multidimensional Aspects of Pain

Present Pain

In women with RRMS, higher means were found with respect to present-pain intensity on the VAS (mean 5.1 ± 2.6, p = .02) and PPI (mean 2.8 ± 1.3, p = .03) versus the VAS (mean 2.8 ± 1.9) and PPI (mean 1.7 ± 0.8) in healthy women.

Present Pattern of Pain. Women with RRMS (n = 9, 69.2%) described their present pattern of pain with the word constant, whereas healthy women (n = 7, 53.9%) described their present pattern of pain with the word intermittent. No significant differences were noted in present pattern of pain between women with RRMS and healthy women (χ2 = 2.96, df = 2, p = .28).

Present-pain Descriptors. The majority of the women in the study chose the sensory word aching and the affective words tiring-exhausting to describe their pain. No significant differences were noted in present-pain descriptors between women with RRMS and healthy women (all p-values were .13 or greater). Likewise, no differences existed in pain-intensity descriptors in women with RRMS (mild: 31.1%, moderate: 31.1%) and healthy women (mild: 23.1%, moderate: 38.5%; p = .87).

Pain over the Last 7 Days

Average Pain Intensity Over the Last 7 Days. Figure 1 depicts the median average pain intensity for women with RRMS and healthy women. Women with RRMS (n = 27) reported higher average pain intensity over the last 7 days compared with healthy women (n = 17; p = .001).

Median Pain Intensity over the Last 7 Days in Women with Relapsing-Remitting Multiple Sclerosis (RRMS) and Healthy Women

Pain Location Over the Last 7 Days. Three pain locations were identified on the body diagram of the BPI-LF as most frequent over the last 7 days in all women: (a) back (65.8%), (b) legs (62.7%), and (c) head/neck (52.3%). Women with RRMS who reported pain over the last 7 days marked their pain primarily in the back and legs. Healthy women who reported pain over the last 7 days typically marked the head/neck and legs. A significant difference existed in pain location over last 7 days between women with RRMS and healthy women (p = .02; Table 3 ).

Pain Interference Over Last 7 Days. Women with RRMS reported higher median pain interference than did healthy women (Fig 2). In particular, women with RRMS more often reported that pain interfered with general activities, mood, sleep, and other life situations than did healthy women (p = .0008).

Median Pain Interference over the Last 7 Days in Women with Relapsing-Remitting Multiple Sclerosis (RRMS) and in Healthy Women

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.

processing....