Antioxidants Used in Skin Care Formulations

I. Bogdan Allemann, MD; L. Baumann, MD

Disclosures

Skin Therapy Letter. 2008;13(7):5-8. 

In This Article

Coenzyme Q10

Coenzyme Q10 (CoQ10), or ubiquinone, is a fat-soluble antioxidant that is found in all human cells as a component of the respiratory chain, as well as in food, e.g., fish and shellfish. Up to 95% of the body´s energy requirements seem to be provided by CoQ10.18 In vitro studies showed that CoQ10 suppressed the expression of collagenase following ultraviolet A (UVA) irradiation.19 In human skin, few studies exist on the topical effect of CoQ10. Nevertheless, CoQ10 is a popular topical antioxidant included in several over-the-counter (OTC) cosmetic products. No side-effects with topical application of CoQ10 have been reported to date.

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