Antioxidants Used in Skin Care Formulations

I. Bogdan Allemann, MD; L. Baumann, MD


Skin Therapy Letter. 2008;13(7):5-8. 

In This Article

Grape Seed

Grape seed is extracted from Vitis vinifera and is rich in proanthocyanidins, which belong to the flavonoid family. Proanthocyanidins are potent antioxidants with strong free radical scavenging activities.[47] Grape seed extract has been shown to be an even stronger scavenger of free radicals than vitamins C and E.[48] A possible antioxidant mechanism of photoprotection by grape seed proanthocyanidins (GSP) was suggested by Mittal, et al.[49] GSP was shown to inhibit the depletion of antioxidant defense components induced by UVB,[50] and topical application of grape seed extract seems to enhance the sun protection factor in humans.[43] It is included in topical cosmetic formulations for antiaging purposes.


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