The Neutrophilic Dermatoses

David Farhi, MD; Daniel Wallach, MD

Disclosures

Dermatology Nursing. 2008;20(4):274-282. 

In This Article

Erythema Elevatum Diutinum

Crocker and Williams described and coined erythema elevatum diutinum (EED) in 1894 (Crocker & Williams, 1894).

EED is characterized by the presence of a leukocytoclastic vasculitis, a feature that is typically absent in other ND.

EED typically presents with chronic infiltrated red or violaceous papules and plaques, which are often located on the extensor aspects of the four limbs (hands, feet, elbows, and knees), in a bilateral and symmetric pattern (see Figure 4). Acute lesions may appear bullous, necrotic, or hemorrhagic. Chronic lesions are yellowish or brown-infiltrated papules and plaques.

Figure 4.

Erythema elevatum diutinum

Skin pathology shows a dermal neutrophilic infiltrate, fibrin deposition, and a leukocytoclastic vasculitis.

Like SPD, EED is usually rapidly responsive to dapsone 100 mg daily. Refractory cases may be treated by oral steroids (Wilkinson, English, Smith, Wilson-Jones, & Winkelmann, 1992).

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.
Post as:

processing....