Vitamin D and Mood Disorders Among Women: An Integrative Review

Pamela K. Murphy, CNM, MS, IBCLC; Carol L. Wagner, MD


J Midwifery Womens Health. 2008;53(5):440-446. 

In This Article


In summary, despite the development of measurements for 25(OH)D more than 30 years ago, only six research studies comparing mood disorders in women and serum 25(OH)D have been published in the literature in the past 15 years. Although each study has limitations, four of the six studies (each examining a different mood disorder) show a significant association between mood disorders and low vitamin D levels, indicating that some biochemical mechanism may exist between the two variables. These associations warrant further studies, using rigorous methods to examine the influence of vitamin D on specific mood disorders.


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