Predicting Outcomes in Pregnancies of Unknown Location

Emma Kirk; Tom Bourne


Women's Health. 2008;4(5):491-499. 

In This Article

Future Perspective

The International Society of Ultrasound in Obstetrics and Gynecology has created a consensus statement on PULs ( Box 1 ).[22] It states that the women with PULs should initially be managed expectantly and both biochemistry and mathematical models can be used to predict PUL outcome. However, the mathematical models need to be tested prospectively in multicenter trials. Further studies are also required to compare the use of the hCG ratio and progesterone levels in the diagnosis of failing pregnancies. In addition, further attention should be concentrated on reducing the length of follow-up required in women with a PUL. Women classified with PULs can provide a significant workload. Reducing the number of follow-up visits required and the length of follow-up would be advantageous for patients and clinical staff alike. Consideration must be given in reducing the number of PULs, since a large number of PULs merely reflects women attending for ultrasound assessment too early in pregnancy.


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