Systemic and Ophthalmic Manifestations of West Nile Virus Infection

Yos Priestley; Marcia Thiel; Steven B. Koevary


Expert Rev Ophthalmol. 2008;3(3):279-292. 

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Expert Commentary

As noted by Kramer et al., one way to improve the diagnosis of WNV would be to use luciferase-reporting flaviviruses for the standard antibody-mediated neutralizing assay.[19] Since the assay would be able to identify the virus within 1 day of infection, the time it would take to confirm a diagnosis of WNV would be shortened considerably. The greatest challenge, however, for clinicians still remains the development of treatments for severe systemic neuropathological symptoms and for ocular symptoms that are not self-limiting.


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