Prescription Omega-3 Fatty Acids and Their Lipid Effects: Physiologic Mechanisms of Action and Clinical Implications

Harold E Bays; Ann P Tighe; Richard Sadovsky; Michael H Davidson


Expert Rev Cardiovasc Ther. 2008;6(3):391-409. 

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Expert Commentary

Omega-3 fatty acids lower TG levels through decreased hepatic secretion of TG-containing lipoproteins and enhanced clearance of TG from circulating TG-containing lipoproteins. In combination with statins, omega-3 fatty acids are effective in improving many lipid parameters beyond that of statin alone, due to their complementary mechanisms of action.


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