Omega-3 fatty acids lower TG levels through decreased hepatic secretion of TG-containing lipoproteins and enhanced clearance of TG from circulating TG-containing lipoproteins. In combination with statins, omega-3 fatty acids are effective in improving many lipid parameters beyond that of statin alone, due to their complementary mechanisms of action.
Expert Rev Cardiovasc Ther. 2008;6(3):391-409. © 2008 Expert Reviews Ltd.
Cite this: Prescription Omega-3 Fatty Acids and Their Lipid Effects: Physiologic Mechanisms of Action and Clinical Implications - Medscape - Mar 01, 2008.