Novel Agents for Intractable Itch

C. B. Lynde; J. N. Kraft, MD; C. W. Lynde, MD, FRCPC


Skin Therapy Letter. 2008;13(1):6-9. 

In This Article

Novel Agents

In the past, if traditional agents were not effective, dermatologists had few other options. The emergence of a new understanding of the pathophysiology of itch has led to novel uses of existing therapies to treat pruritus, which include opiate receptor antagonists, antidepressants, and antiepileptics. The addition of these drugs to the dermatologist's therapeutic arsenal provides options to patients who are inadequate responders to traditional agents. Table 3 provides a summary of these unconventional antipruritic agents.


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