At the same degree of severity of kidney injury and comorbid illnesses, while controlling for other potential confounders, ARF patients with a relative increase of ≥ 101% in the baseline creatinine at the time of the nephrology consultation was an independent predictor of mortality and worse prognosis. The calculation of relative serum creatinine increase could be used as a precise and useful tool in the daily general medical practice, and may be an effective tool to identify those patients who would benefit from an intensive therapy. However, further investigation about timing in nephrology consultation is needed to provide robust knowledge about treatment and prognosis in ARF.
The pre-publication history for this paper can be accessed here: https://www.biomedcentral.com/1471-2369/8/14/prepub
The authors wish to express their gratitude for the contributions made by Dr. Anatole S. Menon Johansson and Dr Zubair Kabir.Abbreviation Notes
ARF = Acute Renal Failure; RIFLE = Risk, Injury, Failure, Loss, End Stage Classification for acute kidney injury; ADQI = Acute Dialysis Quality Initiative; GFR = Glomerular Filtration Rate; AKIN = Acute Kidney Injury Network; MDRD = Modification of Diet in Renal Disease; OR = Odds Ratio; CI = Confidence Intervals.
Jose Ramon Perez-Valdivieso, Department of Anesthesia and Critical Care, Clinica Universitaria, University of Navarra, Pamplona, Spain. Email: firstname.lastname@example.org
BMC Nephrology © 2007 Valdivieso et al; licensee BioMed Central Ltd.
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Cite this: Prognosis and Serum Creatinine Levels In Acute Renal Failure at the Time of Nephrology Consultation: An Observational Cohort Study - Medscape - Sep 26, 2007.