Use of Clindamycin in Pediatric Infections

Marcia L. Buck, Pharm.D., FCCP

Disclosures

Pediatr Pharm. 2008;14(2) 

In This Article

Drug Interactions

Because of its ability to reduce nicotinic receptor depolarization, clindamycin may potentiate the effects of neuromuscular blocking agents. It should be used with caution in patients requiring these drugs over a prolonged period. The combination of erythromycin and clindamycin appears to produce antagonistic effects in vitro, so the concomitant use of these two antibiotics is not recommended.[1,2,3]

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