COMMENTARY

Fat Reduction by Topical Waist Applications May Actually Work


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This is the Medscape Medical Minute. I'm Dr. George Lundberg. So many people struggle with body fat, generalized and localized. How wonderful it would be if a person could rub on a topical cream and make the fat go away. Three researchers at Louisiana State University recently published in the journal Diabetes, Obesity & Metabolism, a randomized, placebo-controlled clinical trial that asked this question. If 50 adult men and women with body mass indices over 27 kg/m were on a prescribed 1200-calorie balanced diet and a walking program, would the addition of the application of 0.5% aminophylline cream to the waist twice a day change BMI and waist circumference? After 12 weeks, the answer was yes, 11 cm less in the cream group and 5 cm less in the control group -- a significant difference. BMI decreased in both groups; waist-to-hip ratios declined; women lost more; aminophylline blood levels were undetectable.[1] Small sample size, but an exciting result, worthy of further study.

I'm Dr. George Lundberg, reporting.


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