Genetic Background of Celiac Disease and Its Clinical Implications

Victorien M. Wolters, M.D.; Cisca Wijmenga, Ph.D.


Am J Gastroenterol. 2008;103(1):190-195. 

In This Article

Other New (Genetic) Developments in CD

Recently, a genetic association between factor V Leiden (FVL) and CD was discovered.[45] A family was described in which the two diseases segregated in all cases as no sibling was affected by only one of the diseases, suggesting that the genetic mutation responsible for the development of CD in this family occurs in a gene very close to FVL on chromosome 1q. Further assessment of this association is needed to unravel the pathogenesis of CD.


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