Evidence-Based Practice: Understanding the Process

Katherine J. Dontje MSN, APRN, BC


Topics in Advanced Practice Nursing eJournal. 2007;7(4) 

In This Article


EBP is the use of current research evidence combined with clinical expertise and patient values to formulate sound interventions.[3] The EBP movement was founded by Professor Archibald Leman Cochrane, CBE, FRCP, FFCM (1909-1988) in 1972. Dr. Cochran, a British epidemiologist, identified a gap between current practices and evidence-based guidelines. Subsequently, the Cochran Review was developed to rigorously evaluate research and synthesize the research evidence, thus facilitating the development of care practices that were based on the most reliable information available.[4]

According to Melynk and Fineout-Overholt, when making an evidence-based clinical decision, the following variables should be considered[4]:

  • Patient's clinical state;

  • Preferences and actions; and

  • Setting and circumstances of the problem.


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