Pregnancy and Rheumatic Diseases

M. Gayed; C. Gordon


Rheumatology. 2007;46(11):1634-1640. 

In This Article


Although there are much fewer data than for RA, pregnancy has been demonstrated to significantly improve peripheral arthritis (as with RA) and uveitis in most patients, but in 25% of patients with predominantly spinal disease it deteriorates in pregnancy. It is difficult to differentiate whether this is due to inflammatory or mechanical changes in pregnancy.[44] During pregnancy there is a change in posture and spinal mobility, partially initiated by relaxin and other hormonal changes during gestation, which cause ligament relaxation. As with other rheumatic disease there is an increased risk of flare postpartum.


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