A Rare Ovarian Tumor -- Sertoli-Leydig Cell Tumor With Heterologous Element

Rimpy Tandon, MD; Poonam Goel, MD; Pradip Kumar Saha, MD; Navneet Takkar, MD; RPS Punia, MD

In This Article


Sertoli-Leydig cell tumor (SLCT) is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. These constitute less than 0.5% of ovarian tumors.[1] Most tumors are unilateral, confined to the ovaries, and are seen during the second and third decades of life. These tumors are characterized by the presence of testicular structures that produce androgens. Hence, many patients have symptoms of virilization depending on the quantity of androgen production. The second characteristic feature of these tumors is the degree of differentiation of structures in them. The presence of these structures determines whether the tumors are benign or malignant.[2] Twenty percent of SLCTs exhibit heterologous elements represented by endodermal elements such as cysts and glands and mesenchymal elements such as bone, cartilage or skeletal muscle. A gastrointestinal structure is rarely reported in these tumors.[3,4] We present the case report of a young woman with an SLCT along with management issues of the disease.


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