Adult Stem Cell Treatment of Scleroderma

Alan Tyndall; Daniel E. Furst

Disclosures

Curr Opin Rheumatol. 2007;19(6):604-610. 

In This Article

Allogeneic Hematopoietic Stem Cell Transplantation

Less is known about this more toxic treatment option, personal communication (GvHD) being a known complication. Three cases are reported, all receiving a reduced intensity nonmyeloablative HSCT.[16,21] In two, a successful response was seen and in a third, TRM occurred at about 1 year from complications relating to acute GvHD. A multidisciplinary consensus group recently published guidelines for allogeneic HSCT in autoimmune disease in general.[22]

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