Constrictive Bronchiolitis Obliterans: The Fibrotic Airway Disorder

Gary R. Epler


Expert Rev Resp Med. 2007;1(1):139-147. 

In This Article

Clinical Course

There are generally two clinical tracks that a patient's course may follow in individuals with the fibrotic obliterative bronchiolitis lesion. The first is a relentless progressive course occurring during several months or slowly over many years. The second is a course of exacerbations over years, sometimes returning to baseline and sometimes progressively worsening after each exacerbation. In unusual situations, the course may be static and stable after the initial presenting episode and, if mild or moderate, the individual will do well. However, if the initial lesion is severe, the naturally occurring yearly decreasing lung function will eventually result in respiratory failure.


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