Severe Cutaneous Adverse Reactions to Drugs

Faith L. Chia; Khai Pang Leong

Disclosures

Curr Opin Allergy Clin Immunol. 2007;7(4):304-309. 

In This Article

Validation of SCORTEN

In 2000, Bastuji-Garin et al.[25] proposed a TEN-specific severity of illness score based on seven prognostic factors including age, presence of malignancy, surface area involved, heart rate, serum urea, bicarbonate and glucose. The SCORTEN was to be calculated within 24 h of admission and accurately predicted the risk of mortality. SCORTEN has since been validated in a US-based patient cohort and has been used as a valuable tool for predicting patient outcome, as well as a basis of comparison for efficacy of treatment.[26]

The performance of SCORTEN has recently been assessed over the first 5 days of hospitalization and found to be good on each day, but predicted the mortality rate most accurately on day 3 of hospitalization. Delay to admission did not appear to affect the prognosis.[27**]

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