Evidence That Two Alkyl Ester Quaternary Ammonium Compounds Lack Substantial Human Skin-Sensitizing Potential

Ian R. Jowsey; Albert M. Kligman; Ian R. White; An Goossens; David A. Basketter

Disclosures

Dermatitis. 2007;18(1):32-39. 

In This Article

Materials

The dialkyl ester of triethanol ammonium methyl sulphate (Chemical Abstracts Service [CAS] number 91-995-81-2) was obtained as Stepantex VRH90 (Stepan Co., Northfield, IL), which was found to be 85.5% TEA-Quat. The di-(hardened tallow fatty acid) ester of 2,3-dihydroxypropyl-trimethyl ammonium chloride (CAS 19467-38-0) was synthesized and was found to be approximately 83% HEQ. Both materials were stored under ambient conditions before being made up at the required concentrations in either distilled water or petrolatum.

Comments

3090D553-9492-4563-8681-AD288FA52ACE
Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.

processing....