Varenicline: The Newest Agent for Smoking Cessation

Lisa A. Potts; Candice L. Garwood

Am J Health Syst Pharm. 2007;64(13):1381-1384.

Drug Interactions

Varenicline has been administered concurrently with warfarin, digoxin, transdermal nicotine, bupropion, cimetidine, and metformin without any clinically significant drug interactions.^[10] Increased rates of nausea were reported when varenicline was given with NRT versus NRT alone.

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Cite this: Varenicline: The Newest Agent for Smoking Cessation - Medscape - Jul 01, 2007.

Abstract and Introduction
Pharmacology of Nicotine
Chemistry and Pharmacology of Varenicline
Pharmacokinetics
Clinical Efficacy
Safety
Drug Interactions
Dosage and Administration
Conclusion
References

Table 1. Cost Comparison of Currently Available Smoking-Cessation Therapies
Drug	Cost ($)/30-Day Supply^a	Availability Status
Varenicline	106.99	Prescription
Bupropion	69.98	Prescription
Nicotine patch	120	Nonprescription
Nicotine gum	46.61-50.43 (108 pieces)	Nonprescription
Nicotine nasal spray	99.97 (3 bottles)	Prescription
Nicotine inhaler	136.99	Prescription
Nicotine lozenge	56.99 (108 pieces)	Nonprescription

^aPrices obtained from www.drugstore.com in November 2006.

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Varenicline: The Newest Agent for Smoking Cessation

Drug Interactions

Tables

References

Authors and Disclosures

Authors and Disclosures

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