An 11-Month-Old Boy With Chronic Diarrhea, Failure to Thrive, and Hepatomegaly

Authors and Disclosures

Steven Liu, MD, Fellow, Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Jonathan E. Markowitz, MD, MSCE, Children's Center for Digestive Health, Associate Professor of Clinical Pediatrics, University of South Carolina School of Medicine, Greenville Hospital System University Medical System, Greenville, South Carolina

Petar Mamula, MD, Director, Endoscopy Suite, Division of GI & Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Assistant Professor of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

David A. Piccoli, MD, Professor of Pediatrics; Chief, Division of Gastroenterology, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Author's email: jmarkowitz@ghs.org

Disclosure: Steven Liu, MD, has disclosed no relevant financial relationships.

Disclosure: Jonathan E. Markowitz, MD, MSCE, has disclosed no relevant financial relationships.

Disclosure: Petar Mamula, MD, has disclosed no relevant financial relationships.

Disclosure: David A. Piccoli, MD, has disclosed no relevant financial relationships.

Suggested Reading I

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• Cipolli M, D'Orazio C, Antonella D, et al. Shwachman's syndrome: pathomorphosis and long-term outcome. J Pediatr Gastroenterol Nutr. 1999;29:265-272.

• Dror Y, Freedman MH. Shwachman-Diamond syndrome. Br J Haematol. 2002;118:701-713.

• Sherman, PM, Mitchell DJ, Cutz E. Neonatal enteropathies: defining the causes of protracted diarrhea of infancy. J Pediatr Gastroenterol Nutr. 2004;38:16-26.

• Shimamura A. Shwachman-Diamond syndrome. Semin Hematol. 2006;43:178-188.

• Stormon MO, Durie PR. Pathophysiologic basis of exocrine pancreatic dysfunction in childhood. J Pediatr Gastroenterol Nutr. 2002;35:8-21.