Cinnamon Supplementation in Patients with Type 2 Diabetes Mellitus

Antony Q. Pham, B.S.; Helen Kourlas, Pharm.D.; David Q. Pham, Pharm.D.


Pharmacotherapy. 2007;27(4):595-599. 

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Data from three published clinical trials suggest that cinnamon has a possible modest effect in lowering plasma glucose levels in patients with poorly controlled type 2 diabetes. However, these trials are limited by small sample sizes, short intervention periods, and lack of dietary standardization. Also, the patient populations in the trials were limited to specific demographics that may not represent the overall patient population with type 2 diabetes. Therefore, cinnamon supplementation may not be effective in all patient populations. Numerous variables must be considered before the beneficial effects of cinnamon can be isolated. Although no adverse effects were reported in these clinical trials, possible long-term effects of cinnamon remain unknown. Therefore, clinicians are strongly urged to refrain from recommending cinnamon supplementation in place of the proven standard of care, which includes lifestyle modifications, oral antidiabetic agents, and insulin therapy.


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