Polycythemia and Increased Erythropoietin in a Patient With Chronic Kidney Disease

Simone Stark; Björn Winkelmann; Christof Kluthe; Jan Roigas; Uwe Querfeld & Dominik Müller


Nat Clin Pract Nephrol. 2007;3(4):222-226. 

In This Article


Background: A 16-year-old white male with a history of obstructive uropathy presented to a pediatric outpatient clinic with a first syncope. At presentation, he had a hemoglobin level of 220 g/l, a serum erythropoietin level of 27.4 U/l and a serum creatinine level of 200.7 µmol/l (2.27 mg/dl).
Investigations: Physical examination, serum laboratory analysis, renal ultrasound, MRI, and 99mTc-MAG3 scintigraphy of the kidneys.
Diagnosis: Chronic renal insufficiency caused by obstructive hydronephrosis and accompanied by increased erythropoietin levels of renal origin and polycythemia.
Management: Serial phlebotomies and laparoscopic removal of the right hydronephrotic kidney.


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