Shilpa Grover, MD; Matthew J. Hamilton , MD; David L. Carr-Locke MD, FRCP, FACG, FASGE Series Editor: David L. Carr-Locke MD, FRCP, FACG, FASGE


May 29, 2007

Approach to Management and Clinical Outcome

Vancomycin enemas were started and treatment with oral vancomycin and intravenous metronidazole were continued without improvement. The patient continued to have abdominal pain and now also had intermittent low-grade fevers. One dose of intravenous immune globulin (IVIG) was administered, with an improvement in diarrhea symptoms within 36 hours of administration. Six weeks after the onset of symptoms, the patient's diarrhea has resolved, with normalization of her white blood cell count and renal function. She has been discharged and is currently on a prolonged taper of oral vancomycin and a 1-month course of oral metronidazole.


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