Silicate-substituted Calcium Phosphate as a Bone Void Filler After Kyphoplasty in a Young Patient With Multiple Compression Fractures due to Osteogenesis Imperfecta Variant

Mitchell A. Hardenbrook, M.D., L.C.D.R., M.C., U.S.N.; Sergio R. Lombardo, D.O., L.T., M.C., U.S.N.


Neurosurg Focus. 2006;21(6) 

In This Article


Silicate-substituted calcium phosphate is an ideal substance to use in conjunction with kyphoplasty for the treatment of compression fractures. In this case report we show that Actifuse gives immediate structural support sufficient to decrease pain from compression fractures in the postoperative period and facilitates bone incorporation due to the osteoinductive properties of the silicate ions, even in metabolically diseased bone. Actifuse is radiopaque and easily visualized using fluoroscopic and radiographic imaging.


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